Chromogranin A / CHGA (Neuroendocrine Marker) Antibody, Rabbit, Polyclonal
Biozol Catalog Number:
NBT-1113-RBP14-P0
Supplier Catalog Number:
1113-RBP14-P0
Alternative Catalog Number:
NBT-1113-RBP14-P0-20,NBT-1113-RBP14-P0-100
Manufacturer:
NeoBiotechnologies
Host:
Rabbit
Category:
Antikörper
Application:
ELISA, FC, IF, IHC
Species Reactivity:
Human
Immunogen:
Recombinant human chromogranin A protein
Alternative Names:
Beta-Granin, CGA, CHGA, Chromogranin A Parathyroid Secretory Protein 1, ER-37, Pancreastatin, Parastatin, Parathyroid Secretory Protein 1, Pituitary Secretory Protein I, SP-I, Vasostatin I or II
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
200ug/ml of Ab Purified by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Application Notes:
ELISA (For coating use Ab at 1-5ug/ml, order Ab without BSA),,Flow Cytometry (1-2ug/million cells), ,Immunofluorescence (1-2ug/ml). ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heatin
Formalin-fixed, paraffin-embedded human Parathyroid stained with Chromogranin A Rabbit Polyclonal Antibody.
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