Recombinant Collagen II (COL2A1) Antibody, Clone: [COL2A1/8882R], Rabbit, Monoclonal

Product Overview

• Article Name: Recombinant Collagen II (COL2A1) Antibody, Clone: [COL2A1/8882R], Rabbit, Monoclonal
• Biozol Catalog Number: NBT-1280-RBM5-P0
• Supplier Catalog Number: 1280-RBM5-P0
• Alternative Catalog Number: NBT-1280-RBM5-P0-20
• Manufacturer: NeoBiotechnologies
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IHC
• Species Reactivity: Human
• Immunogen: Recombinant full-length human COL2A1 protein
• Alternative Names: Alpha 1 type II collagen, AOM, Cartilage collagen, Chondrocalcin, COL11A3, Collagen II alpha 1 polypeptide, SEDC

Product Description

The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function. In cartilage, Collagen Type II constitutes the bulk of the fibril. Sensitization with Collagen Type II induces an erosive polyarthritis in rats, mice and higher primates which can resemble rheumatoid arthritis and relapsing polychrondritis.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [COL2A1/8882R]
• Molecular Weight: 190kDa
• NCBI: 1280
• UniProt: P02458
• Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.