Cystatin A Antibody, IgG2c, Clone: [MSVA-461M], Mouse, Monoclonal

Product Overview

• Article Name: Cystatin A Antibody, IgG2c, Clone: [MSVA-461M], Mouse, Monoclonal
• Biozol Catalog Number: NBT-1475-MSM10-P1
• Supplier Catalog Number: 1475-MSM10-P1
• Alternative Catalog Number: NBT-1475-MSM10-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: IHC
• Species Reactivity: Human
• Immunogen: Recombinant full-length human CSTA protein
• Alternative Names: STF1, STFA, AREI, cstA, Stefin A

Product Description

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [MSVA-461M]
• Molecular Weight: 11kDa
• Isotype: IgG2c
• NCBI: 1475
• UniProt: P01040
• Form: Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide.

Images

Cystatin-A Mouse Monoclonal Antibody (MSVA-461M) tested on many normal and cancer tissues. The immunohistochemistry staining in these tissues aligns with the expression data in Human Protein Atlas.