Desmoglein-3 (Squamous Cell Marker) Antibody, IgG1, Clone: [5H10], Mouse, Monoclonal

Product Overview

• Article Name: Desmoglein-3 (Squamous Cell Marker) Antibody, IgG1, Clone: [5H10], Mouse, Monoclonal
• Biozol Catalog Number: NBT-1830-MSM4-P1
• Supplier Catalog Number: 1830-MSM4-P1
• Alternative Catalog Number: NBT-1830-MSM4-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: FC, IF, WB
• Species Reactivity: Human
• Immunogen: Recombinant human DSG3 extracellular protein fragment
• Alternative Names: 130kDa pemphigus vulgaris antigen (PVA), Balding (Bal), Cadherin family member 6 (CDHF6), Desmoglein-3 (DSG3)

Product Description

Recognizes a protein of 130kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members are identified and all are members of the cadherin cell adhesion molecule superfamily.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [5H10]
• Molecular Weight: 130kDa
• Isotype: IgG1
• NCBI: 1830
• UniProt: P32926
• Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Images

SDS-PAGE Analysis of Purified Desmoglein-3 Monoclonal Antibody (5H10). Confirmation of Integrity and Purity of Antibody.