EGFR (Epidermal Growth Factor Receptor) Antibody, IgG2a, Clone: [B1D8], Mouse, Monoclonal

Product Overview

• Article Name: EGFR (Epidermal Growth Factor Receptor) Antibody, IgG2a, Clone: [B1D8], Mouse, Monoclonal
• Biozol Catalog Number: NBT-1956-MSM2-P0
• Supplier Catalog Number: 1956-MSM2-P0
• Alternative Catalog Number: NBT-1956-MSM2-P0-20,NBT-1956-MSM2-P0-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: FC
• Species Reactivity: Human
• Immunogen: Microsomes from A431 cells.
• Alternative Names: Erbb1, ERBB1, Errp, HER1, mENA, PIG61, Proto-oncogene c-ErbB-1, Receptor Tyrosine Protein Kinase, ErbB1, Urogastrone, wa2, Wa5

Product Description

This antibody reacts with the extracellular domain of EGFR and blocks the EGF/TGFinduced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [B1D8]
• Molecular Weight: ~170kDa (wild type) and ~145kDa (vIII variant)
• Isotype: IgG2a
• NCBI: 1956
• UniProt: P00533
• Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Monoclonal Antibody

Application Notes

• Application Notes: Affinity Purification (For coupling, order Ab without BSA), Blocks Ligand-induced Activation of EGFR, Inhibits Proliferation of A431 cells (Order Ab without sodium azide), Arrests Tumor Growth in vivo (Order Ab without BSA &Azide), Immunoprecipitation (1

Images

SDS-PAGE Analysis of Purified EGFR Mouse Monoclonal Antibody (B1D8). Confirmation of Integrity and Purity of Antibody.