Recombinant Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) Antibody, Clone: [MSVA-648R], Rabbit, Monoclonal

Product Overview

• Article Name: Recombinant Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) Antibody, Clone: [MSVA-648R], Rabbit, Monoclonal
• Biozol Catalog Number: NBT-2006-RBM6-P0
• Supplier Catalog Number: 2006-RBM6-P0
• Alternative Catalog Number: NBT-2006-RBM6-P0-20
• Manufacturer: NeoBiotechnologies
• Host: Rabbit
• Category: Antikörper
• Application: IHC
• Species Reactivity: Human
• Immunogen: Recombinant full-length human Elastin protein
• Alternative Names: Elastin, ELN, SVAS, Tropoelastin, WBS, WS

Product Description

Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries.It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticityto the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [MSVA-648R]
• Molecular Weight: 70kDa
• NCBI: 2006
• UniProt: P15502
• Form: Ab produced in HEK293 cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide.

Images

Elastin Rabbit Recombinant Monoclonal Antibody (MSVA-648R) tested on many normal and cancer tissues. The immunohistochemistry staining in these tissues aligns with the expression data in Human Protein Atlas.