TIGIT / VSTM3 / VSIG9 (Immune Checkpoint for Cancer) Antibody, IgG2b, Clone: [TIGIT/3106], Mouse, Monoclonal

Product Overview

• Article Name: TIGIT / VSTM3 / VSIG9 (Immune Checkpoint for Cancer) Antibody, IgG2b, Clone: [TIGIT/3106], Mouse, Monoclonal
• Biozol Catalog Number: NBT-201633-MSM6-B1
• Supplier Catalog Number: 201633-MSM6-B1
• Alternative Catalog Number: NBT-201633-MSM6-B1-0.5,NBT-201633-MSM6-B1-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: ELISA, IHC
• Species Reactivity: Human
• Immunogen: Recombinant fragment (around aa 22-141) of human TIGIT protein (exact sequence is proprietary)
• Alternative Names: T-cell immunoreceptor with Ig and ITIM domains, V-set and immunoglobulin domain containing 9 (VSIG9), V-set and transmembrane domain containing 3 (VSTM3), Washington University Cell Adhesion Molecule (WUCAM)

Product Description

TIGIT is a checkpoint inhibitor which binds with high affinity to the poliovirus receptor (PVR), causing increased IL10 secretion, decreased IL12B secretion. TIGIT binding to PVR also causes the suppression of T cell activation by promoting the generatio

Product Properties

• Clonality: Monoclonal
• Clone Designation: [TIGIT/3106]
• Molecular Weight: 26kDa
• Isotype: IgG2b
• NCBI: 201633
• UniProt: Q495A1
• Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Monoclonal Antibody

Application Notes

• Application Notes: Immunohistochemistry (Formalin-fixed) (2-4ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 &degC followed by cooling at RT for 20 minutes),Optimal diluti