Estrogen Receptor (Marker of Estrogen Dependence) Antibody, IgG2a, Clone: [ESR1/420], Mouse, Monoclonal

Product Overview

• Article Name: Estrogen Receptor (Marker of Estrogen Dependence) Antibody, IgG2a, Clone: [ESR1/420], Mouse, Monoclonal
• Biozol Catalog Number: NBT-2099-MSM4-P1ABX
• Supplier Catalog Number: 2099-MSM4-P1ABX
• Alternative Catalog Number: NBT-2099-MSM4-P1ABX-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: FC, IF
• Species Reactivity: Human
• Immunogen: Recombinant human ESR1 protein (aa290-560)
• Alternative Names: Estrogen Receptor alpha delta 4*5,6,7*/654 isoform, Estrogen Receptor alpha delta 4 +49 isoform, Nuclear receptor subfamily 3 group A member 1

Product Description

This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this MAb is mapped between aa300-550. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [ESR1/420]
• Molecular Weight: ~67kDa
• Isotype: IgG2a
• NCBI: 2099
• UniProt: P03372
• Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Monoclonal Antibody

Application Notes

• Application Notes: Flow Cytometry (1-2ug/million cells), ,Immunofluorescence (1-2ug/ml), ,Optimal dilution for a specific application should be determined.

Images

SDS-PAGE Analysis of Purified Estrogen Receptor Mouse Monoclonal Antibody (ESR1/420). Confirmation of Integrity and Purity of Antibody.