MART-1 / Melan-A / MLANA (Melanoma Marker) Antibody, IgG1, Clone: [MSVA-901M+], Mouse, Monoclonal

Product Overview

• Article Name: MART-1 / Melan-A / MLANA (Melanoma Marker) Antibody, IgG1, Clone: [MSVA-901M+], Mouse, Monoclonal
• Biozol Catalog Number: NBT-2315-MSM25-P0
• Supplier Catalog Number: 2315-MSM25-P0
• Alternative Catalog Number: NBT-2315-MSM25-P0-20
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: IHC
• Species Reactivity: Human
• Immunogen: Recombinant hMART-1 protein
• Alternative Names: Antigen LB39-AA, Antigen SK29-AA, Melanoma antigen recognized by T-cells 1, MLAN-A, MLANA

Product Description

This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [MSVA-901M+]
• Molecular Weight: 20-22kDa (doublet)
• Isotype: IgG1
• NCBI: 2315
• UniProt: Q16655
• Form: Ab purified from Bioreactor Concentrate by Protein G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide.