Recombinant fragment (around aa100-250) of human PRAME protein (exact sequence is proprietary)
Alternative Names:
Cancer/testis antigen 130, CT130, MAPE, Melanoma antigen preferentially expressed in tumors, OIP 4, OIP-4, OIP4, OPA interacting protein 4, Opa interacting protein OIP4, OPA-interacting protein 4, PRAME, Preferentially expressed antigen in melanoma, Pref
Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis. This gene encodes an ant
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
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