Recombinant Ferritin, Light Chain (Node-Negative Breast Tumor Prognostic Marker) Antibody, IgG1, Clone: [rFTL/1386], Mouse, Monoclonal

Product Overview

• Article Name: Recombinant Ferritin, Light Chain (Node-Negative Breast Tumor Prognostic Marker) Antibody, IgG1, Clone: [rFTL/1386], Mouse, Monoclonal
• Biozol Catalog Number: NBT-2512-MSM8-P0
• Supplier Catalog Number: 2512-MSM8-P0
• Alternative Catalog Number: NBT-2512-MSM8-P0-20,NBT-2512-MSM8-P0-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human
• Immunogen: Recombinant full-length human FTL protein
• Alternative Names: Ferritin L chain, Ferritin L subunit, Ferritin light chain, Ferritin light polypeptide, FTL, LFTD, NBIA3

Product Description

Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [rFTL/1386]
• Molecular Weight: 19-25kDa
• Isotype: IgG1
• NCBI: 2512
• UniProt: P02792
• Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Recombinant Monoclonal Antibody

Application Notes

• Application Notes: Western Blot (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20

Images

Formalin-fixed, paraffin-embedded human kidney stained with Ferritin, Light Chain Recombinant Mouse Monoclonal Antibody (rFTL/1386).

SDS-PAGE Analysis of Purified Ferritin, Light Chain Recombinant Mouse MAb (rFTL/1386). Confirmation of Integrity and Purity of Antibody

Western Blot Analysis of human Kidney tissue lysate using Ferritin, Light Chain Mouse Monoclonal Antibody (FTL/1386).

Western blot analysis of Jurkat cell lysate using TAG-72 Recombinant Rabbit Monoclonal Antibody (TAG72/8317R).

Western blot analysis of A-431 cell lysate using FTL Mouse Monoclonal Antibody (FTL/1386).

Western blot analysis of A-431 cell lysate using FTL Mouse Monoclonal Antibody (FTL/1387).

Western blot analysis of A-431 cell lysate using FTL Mouse Monoclonal Antibody (FTL/1388).

Western blot analysis of A-431 cell lysate using FTL Mouse Monoclonal Antibody (FTL/1389).

Western blot analysis of A-431 cell lysate using FTL Mouse Monoclonal Antibody (FTL/3100).

Western blot analysis of A-431 cell lysate using FTL Recombinant Mouse Monoclonal Antibody (rFTL/1388).

Western blot analysis of Human Brain, Human Kidney, Human Liver, Human Lung, Human Spleen, A431 and HeLa lysates using FTL Recombinant Mouse Monoclonal Antibody (rFTL/1386).

Western blot analysis of A-431 cell lysate using FTL Recombinant Mouse Monoclonal Antibody (rFTL/1386).

Western blot analysis of A-431 cell lysate using FTL Recombinant Rabbit Monoclonal Antibody (FTL/2338R).

Western blot analysis of A-431 cell lysate using FTL Recombinant Rabbit Monoclonal Antibody (FTL/3872R).