Recombinant fragment (around aa100-200) of human GFAP protein (exact sequence is proprietary)
Alternative Names:
Astrocyte or Intermediate Filament Protein, Glial Fibrillary Acidic Protein (GFAP)
This MAb recognizes a protein of ~50kDa which is identified as Glial Fibrillary Acidic Protein (GFAP). It shows no cross-reaction with other intermediate filament proteins. GFAP is specifically found in astroglia. GFAP is a very popular marker for localizing benign astrocyte and neoplastic cells of glial origin in the central nervous system. Antibody to GFAP is useful in differentiating primary gliomas from metastatic lesions in the brain and for documenting astrocytic differentiation in tumors outside the CNS.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human brain stained with GFAP Recombinant Rabbit Monoclonal Antibody (GFAP/8255R). Inset: PBS instead of primary antibody, secondary only negative control.
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