Blood Group Antigen H Type 2 (CD173) Antibody, IgM, Clone: [19-OLE], Mouse, Monoclonal

Product Overview

• Article Name: Blood Group Antigen H Type 2 (CD173) Antibody, IgM, Clone: [19-OLE], Mouse, Monoclonal
• Biozol Catalog Number: NBT-28-MSM1-P1BX
• Supplier Catalog Number: 28-MSM1-P1BX
• Alternative Catalog Number: NBT-28-MSM1-P1BX-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: IF, IHC
• Species Reactivity: Human
• Immunogen: Mucinous colonic adenocarcinoma
• Alternative Names: A transferase, ABO, B transferase, CD173, Fucosylglycoprotein 3-alpha-galactosyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, Histo-blood group A transferase, Histo-blood group B transferase, NAGAT

Product Description

19-OLE reacts with the blood group H type 2 antigens, trisaccharide Fuc1-2Gal1-4GlcNAc1 of human origin. This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. It is expressed on endothelial cells, epithelial cells and granulocytes. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas, and colon carcinomas.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [19-OLE]
• Molecular Weight: Multiple
• Isotype: IgM
• NCBI: 28
• UniProt: P16442
• Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Images

Formalin-paraffin human Colon Carcinoma stained with Blood Group Antigen H Type 2 MAb (19-OLE)