Recombinant PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target) Antibody, Clone: [ZR3], Rabbit, Monoclonal

Product Overview

• Article Name: Recombinant PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target) Antibody, Clone: [ZR3], Rabbit, Monoclonal
• Biozol Catalog Number: NBT-29126-RBM17-P1
• Supplier Catalog Number: 29126-RBM17-P1
• Alternative Catalog Number: NBT-29126-RBM17-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Rabbit
• Category: Antikörper
• Application: IHC
• Species Reactivity: Human
• Immunogen: Recombinant fragment (around aa190-290) of human CD274 protein (exact sequence is proprietary)
• Alternative Names: B7 homolog 1, B7-H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1

Product Description

PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [ZR3]
• Molecular Weight: 37-50kDa
• NCBI: 29126
• UniProt: Q9NZQ7
• Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Images

Formalin-fixed, paraffin-embedded human breast stained with PDL1 Recombinant Rabbit Monoclonal Antibody (ZR3). HIER: Tris/EDTA, pH9.0, 45min. 2°: HRP-polymer, 30min. DAB, 5min.