Annexin A1 / (Hairy Cell Leukemia Marker) Antibody, IgG2a, Clone: [CPTC-ANXA1-1], Mouse, Monoclonal

Article Name:	Annexin A1 / (Hairy Cell Leukemia Marker) Antibody, IgG2a, Clone: [CPTC-ANXA1-1], Mouse, Monoclonal
Biozol Catalog Number:	NBT-301-MSM3-P1
Supplier Catalog Number:	301-MSM3-P1
Alternative Catalog Number:	NBT-301-MSM3-P1-100
Manufacturer:	NeoBiotechnologies
Host:	Mouse
Category:	Antikörper
Application:	IHC, WB
Species Reactivity:	Hamster, Human, Mouse, Rabbit, Rat
Immunogen:	Recombinant full-length human Annexin A1 protein
Alternative Names:	ANXA1, ANX1, Annexin-1, Chromobindin-9, LPC1, p35

The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

Clonality:	Monoclonal
Clone Designation:	[CPTC-ANXA1-1]
Molecular Weight:	38kDa
Isotype:	IgG2a
NCBI:	301
UniProt:	P04083
Form:	200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

	Formal
	Formalin-fixed, paraffin-embedded human Placenta stained with Annexin A1 Mouse Monoclonal Antibody (CPTC-ANXA1-1).
	SDS-PAGE Analysis of Purified Annexin A1 Mouse Monoclonal Antibody (CPTC-ANXA1-1). Confirmation of Purity and Integrity of Antibody.
	Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with Annexin A1 Mouse Monoclonal Antibody (CPTC-ANXA1-1).
	Western Blot Analysis of human A549 cell lysate using Annexin A1 Mouse Monoclonal Antibody (CPTC-ANXA1-1).
	Western Blot Analysis of Human Lung, Mouse Lung, Rat Lung, Hamster Lung, Guinea pig Lung and Rabbit Lung tissue lysates using Annexin A1 Recombinant Mouse Monoclonal Antibody (rANXA1/4310).
	Western Blot Analysis of Human Lung, Mouse Lung, Rat Lung, Hamster Lung, Guinea pig Lung and Rabbit Lung tissue lysates using Annexin A1 Recombinant Mouse Monoclonal Antibody (rANXA1/6451).
	Western Blot Analysis of Human Lung, Mouse Lung, Rat Lung, Hamster Lung, Guinea pig Lung and Rabbit Lung tissue lysates using Annexin A1 Recombinant Mouse Monoclonal Antibody (rANXA1/9145).
	Western Blot Analysis of Human Lung, Mouse Lung, Rat Lung, Hamster Lung, Guinea pig Lung and Rabbit Lung tissue lysates using Annexin A1 Mouse Monoclonal Antibody (CPTC-ANXA1-1).
	Western Blot Analysis of Human Intestine, Human Lung and A549 lysates using Annexin A1 Mouse Monoclonal Antibody (CPTC-ANXA1-1).
	Western Blot Analysis of Human Lung, Mouse Lung, Rat Lung, Hamster Lung, Guinea pig Lung and Rabbit Lung tissue lysates using Annexin A1 Recombinant Mouse Monoclonal Antibody (rANXA1/9145).