Annexin A1 / (Hairy Cell Leukemia Marker) Antibody, IgG1, Clone: [ANXA1/3728], Mouse, Monoclonal

Product Overview

• Article Name: Annexin A1 / (Hairy Cell Leukemia Marker) Antibody, IgG1, Clone: [ANXA1/3728], Mouse, Monoclonal
• Biozol Catalog Number: NBT-301-MSM8-P1
• Supplier Catalog Number: 301-MSM8-P1
• Alternative Catalog Number: NBT-301-MSM8-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: ELISA, FC, IF
• Species Reactivity: Human
• Immunogen: Mixture of native proteins from human bone tissues
• Alternative Names: ANXA1, ANX1, Annexin-1, Chromobindin-9, LPC1, p35

Product Description

The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [ANXA1/3728]
• Molecular Weight: 35kDa
• Isotype: IgG1
• NCBI: 301
• UniProt: P04083
• Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.