Tenascin C (Stromal Marker for Epithelial Malignancy) Antibody, IgG1, Clone: [T2H5], Mouse, Monoclonal

Product Overview

• Article Name: Tenascin C (Stromal Marker for Epithelial Malignancy) Antibody, IgG1, Clone: [T2H5], Mouse, Monoclonal
• Biozol Catalog Number: NBT-3371-MSM1-P1
• Supplier Catalog Number: 3371-MSM1-P1
• Alternative Catalog Number: NBT-3371-MSM1-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: IHC
• Species Reactivity: Human
• Immunogen: Human breast carcinoma
• Alternative Names: Cytotactin, Glioma-associated-extracellular matrix antigen, GMEM, GP 150-225, Hexabrachion (HXB), JI, Myotendinous antigen, Neuronectin, TNC

Product Description

In Western blotting, it reacts with two bands of ~MW of 210kDa and 300kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linkedhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [T2H5]
• Molecular Weight: 210kDa and 300kDa
• Isotype: IgG1
• NCBI: 3371
• UniProt: P24821
• Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Images

Formalin-fixed, paraffin-embedded human Lung Carcinoma stained with Tenascin C Monoclonal Antibody (T2H5). Note staining of connective tissue.