Recombinant CD54 / ICAM-1 Antibody, Clone: [ICAM1/9379R], Rabbit, Monoclonal

Product Overview

• Article Name: Recombinant CD54 / ICAM-1 Antibody, Clone: [ICAM1/9379R], Rabbit, Monoclonal
• Biozol Catalog Number: NBT-3383-RBM13-P1ABX
• Supplier Catalog Number: 3383-RBM13-P1ABX
• Alternative Catalog Number: NBT-3383-RBM13-P1ABX-100
• Manufacturer: NeoBiotechnologies
• Host: Rabbit
• Category: Antikörper
• Application: IHC
• Species Reactivity: Human
• Immunogen: IL-1B activated human vascular endothelial cells expressing ICAM-1.
• Alternative Names: CD54, Cell surface glycoprotein P3.58, Human rhinovirus receptor, ICAM-1, Intercellular adhesion molecule 1, Ly 47, Major group rhinovirus receptor, MALA2, MyD10, Surface antigen of activated B cells

Product Description

Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [ICAM1/9379R]
• Molecular Weight: 85-115kDa
• NCBI: 3383
• UniProt: P05362
• Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.