Recombinant STING1 / TMEM173 Antibody, Clone: [STING1/8187R], Rabbit, Monoclonal

Product Overview

• Article Name: Recombinant STING1 / TMEM173 Antibody, Clone: [STING1/8187R], Rabbit, Monoclonal
• Biozol Catalog Number: NBT-340061-RBM13-P1
• Supplier Catalog Number: 340061-RBM13-P1
• Alternative Catalog Number: NBT-340061-RBM13-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Rabbit
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human
• Immunogen: Recombinant fragment (around aa190-290) of human TMEM173 protein (exact sequence is proprietary)
• Alternative Names: Endoplasmic reticulum interferon stimulator, ERIS, hMITA, hSTING, Mediator of IRF3 activation, MITA, NET23, MPYS, Mitochondrial mediator of IRF3 activation, N terminal methionine proline tyrosine serine plasma membrane tetraspanner, Stimulator of interferon genes protein, Transmembrane protein 173

Product Description

TMEM17 (transmembrane protein 173) is a 379 amino acid protein encoded by a gene mapping to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [STING1/8187R]
• Molecular Weight: 37-50kDa
• NCBI: 340061
• UniProt: Q86WV6
• Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.