Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.
Clonality:
Monoclonal
Clone Designation:
[ITGAV/1610]
Molecular Weight:
150-160kDa under non-reducing conditions. Under reducing conditions|it is cleaved into 2 bands of about 125-130kDa +20-25kDa.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis of Purified CD51 / Integrin V Mouse Monoclonal Antibody (ITGAV/1610). Confirmation of Purity and Integrity of Antibody.
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