This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Western Blot Analysis o
Formalin-fixed, paraffin-embedded human Lung Ca stained with Cytokeratin 18 Mouse Monoclonal Antibody (Cocktail).
Formalin-fixed, paraffin-embedded human Thyroid Ca stained with Cytokeratin 18 Mouse Monoclonal Antibody (Cocktail).
Western Blot Analysis of human HCT116 cell lysate using Cytokeratin 18 Mouse Monoclonal Antibody (Cocktail).
Formalin-fixed, paraffin-embedded human colon carcinoma stained with Cytokeratin 18 Mouse Monoclonal Antibody (Cocktail).
Formalin-fixed, paraffin-embedded human Cervical Ca stained with Cytokeratin 18 Mouse Monoclonal Antibody (Cocktail).
Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with Cytokeratin 18 Mouse Monoclonal Antibody (Cocktail).
Flow Cytometric Analysis of PFA-fixed HeLa cells using Cytokeratin 18 Mouse Monoclonal Antibody (Cocktail) followed by Goat anti-Mouse IgG-CF488 (Blue), Isotype Control (Red)
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