Recombinant human LMO2 protein fragment (around aa 23-140) (exact sequence is proprietary)
Alternative Names:
Cysteine-rich protein TTG-2, LIM domain only protein 2, LMO-2, RBTN L1, RBTN2,Rhombotinlike 1, Rhombotin-2 (RHOM2), T-cell translocation protein 2, TTG2
The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma.The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin.LMO2 is useful in differentiating follicular lymphoma (LMO2+) from nodal marginal zone lymphoma (LM02-). It also is positive in Hodgkin s and Burkitt s lymphomas.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human follicular lymphoma stained with LMO2 Mouse Monoclonal Antibody (LMO2/1972).
Formalin-fixed, paraffin-embedded human pancreas stained with LMO2 Mouse Monoclonal Antibody (LMO2/1972).
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