TACSTD2 / TROP2 (Epithelial Marker) Antibody, IgG2b, Clone: [TACSTD2/2151], Mouse, Monoclonal

Catalog Number: NBT-4070-MSM1-B1
Article Name: TACSTD2 / TROP2 (Epithelial Marker) Antibody, IgG2b, Clone: [TACSTD2/2151], Mouse, Monoclonal
Biozol Catalog Number: NBT-4070-MSM1-B1
Supplier Catalog Number: 4070-MSM1-B1
Alternative Catalog Number: NBT-4070-MSM1-B1-0.5,NBT-4070-MSM1-B1-100
Manufacturer: NeoBiotechnologies
Host: Mouse
Category: Antikörper
Application: IHC, WB
Species Reactivity: Human
Immunogen: Recombinant fragment of human TACSTD2 protein (around aa 31-274) (exact sequence is proprietary)
Alternative Names: Cell surface glycoprotein Trop-2, Membrane Component Chromosome 1, Surface Marker 1 (M1S1), Pancreatic Carcinoma Marker Protein GA733-1, TROP2, Tumor-Associated Calcium Signal Transducer 2 (TACSTD2)
TACSTD2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.
Clonality: Monoclonal
Clone Designation: [TACSTD2/2151]
Molecular Weight: 40kDa
Isotype: IgG2b
NCBI: 4070
UniProt: P09758
Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Monoclonal Antibody
Application Notes: Western Blot (1-2ug/ml), ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 C followed by cooling at RT for 20