Recombinant EpCAM / CD326 (Epithelial Marker) Antibody, Clone: [MSVA-326R], Rabbit, Monoclonal

Product Overview

• Article Name: Recombinant EpCAM / CD326 (Epithelial Marker) Antibody, Clone: [MSVA-326R], Rabbit, Monoclonal
• Biozol Catalog Number: NBT-4072-RBM45-P1
• Supplier Catalog Number: 4072-RBM45-P1
• Alternative Catalog Number: NBT-4072-RBM45-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Rabbit
• Category: Antikörper
• Application: IHC
• Species Reactivity: Human
• Immunogen: Recombinant fragment from the extracellular domain of human EpCAM protein (around aa100-224) (exact sequence is proprietary)
• Alternative Names: Adenocarcinoma-associated Antigen, Cell Surface Glycoprotein Trop-1, EGP2, EGP314, EGP40, Epithelial Cell Adhesion Molecule, Epithelial Glycoprotein 314, ESA, KSA, TACD1, TROP1, Tumor-associated Calcium Signal Transducer 1 (TACSTD1)

Product Description

Epitope of this MAb is mapped between aa 202-212 of EGP40, which is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. Antibody to Ep-CAM has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [MSVA-326R]
• Molecular Weight: 40-43kDa
• NCBI: 4072
• UniProt: P16422
• Form: Ab produced in HEK293 cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide.

Images

Epithelial cell adhesion molecule Rabbit Recombinant Monoclonal Antibody (MSVA-326R) tested on many normal and cancer tissues. The immunohistochemistry staining in these tissues aligns with the expression data in Human Protein Atlas.