Recombinant MCM7 (Proliferation Marker) Antibody, Clone: [MSVA-507R], Rabbit, Monoclonal

Product Overview

• Article Name: Recombinant MCM7 (Proliferation Marker) Antibody, Clone: [MSVA-507R], Rabbit, Monoclonal
• Biozol Catalog Number: NBT-4176-RBM10-P1
• Supplier Catalog Number: 4176-RBM10-P1
• Alternative Catalog Number: NBT-4176-RBM10-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Rabbit
• Category: Antikörper
• Application: IHC
• Species Reactivity: Human
• Immunogen: Recombinant human MCM7 protein fragment (aa195-319)
• Alternative Names: CDC47, DNA replication licensing factor MCM7, MCM7 mini chromosome maintenance deficient 7, Mini chromosome Maintenance 7, Mini chromosome maintenance protein 7, P1.1-MCM3, P1CDC47, P85MCM, PNAS146

Product Description

MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [MSVA-507R]
• Molecular Weight: 88kDa
• NCBI: 4176
• UniProt: P33993
• Form: Ab produced in HEK293 cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide.

Images

DNA replication licensing factor MCM7 Rabbit Recombinant Monoclonal Antibody (MSVA-507R) tested on many normal and cancer tissues. The immunohistochemistry staining in these tissues aligns with the expression data in Human Protein Atlas.