Moesin Antibody, IgG1, Clone: [MSN/491], Mouse, Monoclonal

Product Overview

• Article Name: Moesin Antibody, IgG1, Clone: [MSN/491], Mouse, Monoclonal
• Biozol Catalog Number: NBT-4478-MSM1-P1
• Supplier Catalog Number: 4478-MSM1-P1
• Alternative Catalog Number: NBT-4478-MSM1-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: FC, IF, IHC, WB
• Species Reactivity: Human, Rat
• Immunogen: Recombinant full-length human Moesin protein
• Alternative Names: Membrane-organizing extension spike protein, Moesin/anaplastic lymphoma kinase fusion protein, MSN/ALK fusion

Product Description

Recognizes 78kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [MSN/491]
• Molecular Weight: 78kDa
• Isotype: IgG1
• NCBI: 4478
• UniProt: P26038
• Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Images

Formalin-fixed, paraffin-embedded Rat Lung

Formalin-fixed, paraffin-embedded human Placenta stained with Moesin Mouse Monoclonal Antibody (MSN/491).

Formalin-fixed, paraffin-embedded human Melanoma stained with Moesin Mouse Monoclonal Antibody (MSN/491).

Formalin-fixed, paraffin-embedded Rat Lung stained with Moesin Mouse Monoclonal Antibody (MSN/491).

Formalin-fixed, paraffin-embedded Rat Colon stained with Moesin Mouse Monoclonal Antibody (MSN/491).

Western blot of HT29 cell lysate using Moesin Mouse Monoclonal Antibody (MSN/491).

SDS-PAGE Analysis Purified Moesin Mouse Monoclonal Antibody (MSN/491).

Immunofluorescence Analysis of PFA-fixed HeLa cells labeling Moesin with Moesin Mouse Monoclonal Antibody (MSN/491) followed by Goat anti-Mouse IgG-CF488 (Green). The nuclear counterstain is Reddot (Red)

Flow Cytometric Analysis of K562 cells using Moesin Mouse Monoclonal Antibody (MSN/491) followed by Goat anti-Mouse IgG-CF488 (Blue), Isotype Control (Red).

Western Blot Analysis of human PC3 cell lysate using Mouse Monoclonal Antibody (MSN/491).