Recombinant MUC4 (Mucin 4 / Gastric Mucin) Antibody, Clone: [MUC4/8660R], Rabbit, Monoclonal

Catalog Number: NBT-4585-RBM8-P1
Article Name: Recombinant MUC4 (Mucin 4 / Gastric Mucin) Antibody, Clone: [MUC4/8660R], Rabbit, Monoclonal
Biozol Catalog Number: NBT-4585-RBM8-P1
Supplier Catalog Number: 4585-RBM8-P1
Alternative Catalog Number: NBT-4585-RBM8-P1-100
Manufacturer: NeoBiotechnologies
Host: Rabbit
Category: Antikörper
Application: IHC
Species Reactivity: Human
Immunogen: Recombinant fragment (around aa 1729-1860) of human MUC4 protein (exact sequence is proprietary)
Alternative Names: Ascites sialoglycoprotein 1 / 2, ASGP, ASGP-1, ASGP-2, MUC-4, MUC4, Mucin 4 cell surface associated, Mucin 4 tracheobronchial, Mucin-4 beta chain, Pancreatic adenocarcinoma mucin, Testis mucin, Tracheobronchial mucin
The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. MUC-4 transcripts have been detected in normal respiratory epithelium and lung. MUC-4 is a very specific (100%) and sensitive (90%) marker of lung adenocarcinomas and is negative for mesotheliomas. Reportedly, MUC-4 expression in invasive ductal carcinoma of the pancreas is an independent factor for poor prognosis.
Clonality: Monoclonal
Clone Designation: [MUC4/8660R]
Molecular Weight: 235kDa
NCBI: 4585
UniProt: Q99102
Form: 200ug/ml of Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis of Purified Mucin 4 Recombinant Rabbit Monoclonal Antibody (MUC4/8660R). Confirmation of Purity and Integrity of Antibody.
Formalin-fixed, paraffin-embedded human colon stained with Mucin 4 Recombinant Rabbit Monoclonal Antibody (MUC4/8660R). Inset: PBS instead of primary antibody, secondary only negative control.