Recombinant fragment (around aa1150-1350) of human MYH7 protein (exact sequence is proprietary)
Alternative Names:
Beta myosin heavy chain, cardiac muscle beta isoform, CMD1S, CMH1, MPD1, MyHC-beta, MyHC-slow, MYHCB, Myopathy, distal 1, Myosin heavy chain (AA 1-96), Myosin heavy chain slow isoform, Myosin heavy chain, cardiac muscle beta isoform, Myosin, heavy chain 7, cardiac muscle, beta, Myosin, heavy polypeptide 7, cardiac muscle, beta, Myosin-7, Rhabdomyosarcoma antigen MU RMS 40.7A, SPMD, SPMM
Myosin heavy chains are ubiquitous Actin-based motor proteins that convert the chemical energy derived from ATP hydrolysis into the mechanical energy that drives diverse motile processes in eukaryotic cells, including cytokinesis, vesicular transport and cellular locomotion. Muscle myosin is a heterohexamer consisting of two myosin heavy chains and two associated nonidentical pairs of myosin light chains. The seven myosin heavy chain isoforms that predominate in mammalian skeletal muscles include two developmental isoforms, MHC-embryonic (MYH3) and MHC-perinatal (MYH8), three adult skeletal muscle isoforms, MHC IIa (MYH2), MHC IIb (MYH4) and MHC IIx/d (MYH1), and MHC-/slow (MYH7 or MHC-), which is also expressed in cardiac muscle. Research indicates that mutations of the MYH7 gene causes hypertrophic cardiomyopathy.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human skeletal muscle stained with MYH7 Mouse Monoclonal Antibody (MYH7/9183). Inset: PBS instead of primary antibody, secondary only negative control.
SDS-PAGE Analysis of Purified MYH7 Mouse Monoclonal Antibody (MYH7/9183). Confirmation of Purity and Integrity of Antibody.
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