Recombinant CD56 / NCAM1 / NKH1 (Neuronal Cell Marker) Antibody, Clone: [MSVA-056R], Rabbit, Monoclonal

Product Overview

• Article Name: Recombinant CD56 / NCAM1 / NKH1 (Neuronal Cell Marker) Antibody, Clone: [MSVA-056R], Rabbit, Monoclonal
• Biozol Catalog Number: NBT-4684-RBM50-P0
• Supplier Catalog Number: 4684-RBM50-P0
• Alternative Catalog Number: NBT-4684-RBM50-P0-20
• Manufacturer: NeoBiotechnologies
• Host: Rabbit
• Category: Antikörper
• Application: IHC
• Species Reactivity: Human
• Immunogen: Recombinant fragment (around aa200-400) of human NCAM1 (CD56) protein (exact sequence is proprietary)
• Alternative Names: NCAM, Leu-19, NKH1, MSK39, NCAM120, NCAM140, NCAM180, Neural Cell Adhesion Molecule

Product Description

This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [MSVA-056R]
• Molecular Weight: 145 and 125kDa|180
• NCBI: 4684
• UniProt: P13591
• Form: Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide.

Images

Neural cell adhesion molecule 1 Rabbit Recombinant Monoclonal Antibody (MSVA-056R) tested on many normal and cancer tissues. The immunohistochemistry staining in these tissues aligns with the expression data in Human Protein Atlas.