Human recombinant NKX2.2 protein fragment (around aa1-119) (exact sequence is proprietary)
Alternative Names:
Homeobox protein NK-2 homolog B, NK2 transcription factor like protein B, NK2 transcription factor related locus 2, NKX22, Nkx2b, tinman
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human Ewing&apos,s Sarcoma stained with NKX2.2 Mouse Recombinant Monoclonal Antibody (rNX2/1523).
SDS-PAGE Analysis of Purified NKX2.2 Mouse Recombinant Monoclonal Antibody (rNX2/1523). Confirmation of Integrity and Purity of Antibody.
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