Progesterone Receptor (Marker of Progestin Dependence) Antibody, IgG1, Clone: [PR501], Mouse, Monoclonal

Product Overview

• Article Name: Progesterone Receptor (Marker of Progestin Dependence) Antibody, IgG1, Clone: [PR501], Mouse, Monoclonal
• Biozol Catalog Number: NBT-5241-MSM3-P1
• Supplier Catalog Number: 5241-MSM3-P1
• Alternative Catalog Number: NBT-5241-MSM3-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human
• Immunogen: Recombinant human Progesterone Receptor protein
• Alternative Names: NR3C3, Nuclear receptor subfamily 3 group C member 3, PGR, PR, PRA, PRB, Progesterone receptor form A, Progesterone receptor form B

Product Description

This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [PR501]
• Molecular Weight: PR-A (81kDa) and PR-B (116kDa).
• Isotype: IgG1
• NCBI: 5241
• UniProt: P06401
• Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Images

Formalin-fixed, paraffin-embedded normal human breast (left) and invasive ductal carcinoma (right) stained with progesterone receptor Ab (PR501).

SDS-PAGE Analysis of Purified PR Monoclonal Antibody (PR501). Confirmation of Integrity and Purity of Antibody