Proteolipid Protein / Myelin PLP Antibody, IgG2a, Clone: [PLP1/4259], Mouse, Monoclonal

Catalog Number: NBT-5354-MSM1-P0
Article Name: Proteolipid Protein / Myelin PLP Antibody, IgG2a, Clone: [PLP1/4259], Mouse, Monoclonal
Biozol Catalog Number: NBT-5354-MSM1-P0
Supplier Catalog Number: 5354-MSM1-P0
Alternative Catalog Number: NBT-5354-MSM1-P0-20,NBT-5354-MSM1-P0-100
Manufacturer: NeoBiotechnologies
Host: Mouse
Category: Antikörper
Application: IHC
Species Reactivity: Bovine, Human, Mouse, Rat, Reptile
Immunogen: Synthetic peptide GRGTKF that recognizes the C terminal region (aa272-277) of myelin proteolipid protein.
Alternative Names: Myelin proteolipid protein, PLP, Lipophilin, PLP1, HLD1, SPG2, PMD, Major myelin proteolipid protein (MMPL), DM20
Proteolipid protein (PLP) is the major myelin protein of the CNS and plays an important role in the formation and maintenance of myelin. PLP may play a role in the compaction and stabilization of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in PLP gene can lead to dysmyelinating diseases. Clone PLP1/4259 is used in the detection of PLP by various analysis methods.
Clonality: Monoclonal
Clone Designation: [PLP1/4259]
Molecular Weight: 23-25kDa
Isotype: IgG2a
NCBI: 5354
UniProt: P60201
Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Monoclonal Antibody
Application Notes: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 &degC followed by cooling at RT for 20 minutes),Optimal diluti
Formalin-fixed, paraffin-embedded human brain stained with Myelin PLP Mouse Monoclonal Antibody (PLP1/4259).
SDS-PAGE Analysis of Purified Myelin PLP Mouse Monoclonal Antibody (PLP1/4259). Confirmation of Integrity and Purity of Antibody.