Recombinant fragment of human IMP3 protein (exact sequence is proprietary)
Alternative Names:
U3 Small Nucleolar Ribonucleoprotein Protein IMP3, BRMS2, MRPS4
Imp3, also known as BRMS2, C15orf12 or MRPS4, is a 184 amino acid protein that contains one S4 RNA-binding domain and is the mammalian homolog of the yeast Imp3 protein. Localized to the nucleus, Imp3 exists as a component of a heterotrimeric complex consisting of MPP10, Imp3 and Imp4 and, in this complex, plays a key role in early cleavage events during pre-18S ribosomal processing. The gene encoding Imp3 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Western blot analysis of HEK293T, MCF7, A549 and K-562 cell lysates using IMP3 Recombinant Rabbit Monoclonal Antibody (IMP3/8985R).
Formalin-fixed, paraffin-embedded human placenta stained with IMP-3 Recombinant Rabbit Monoclonal Antibody (IMP3/8985R) Inset: PBS instead of primary antibody, secondary only negative control.
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