Protein Kinase C alpha / PRKCA Antibody, IgG2a, Clone: [133], Mouse, Monoclonal
Biozol Catalog Number:
NBT-5578-MSM2-P0
Supplier Catalog Number:
5578-MSM2-P0
Alternative Catalog Number:
NBT-5578-MSM2-P0-20,NBT-5578-MSM2-P0-100
Manufacturer:
NeoBiotechnologies
Host:
Mouse
Category:
Antikörper
Application:
IHC, WB
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Full-length protein corresponding to PKC alpha. Recognizes sequence PQFVHPILQSAV at the C terminus at PKCalpha.
Alternative Names:
PKC alpha, PKC-A, PKC-alpha, PKCA, PRKCA, Protein kinase C alpha, Protein kinase C alpha type
Protein Kinase C alpha (PKC(TM)) is involved in the regulation of cell proliferation during cell cycle progression. This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. May play a role in cell motility by phosphorylating CSPG4. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Clone 133 recognizes the (TM) isoform of PKC(TM) and binds to a sequence at the C terminus of PKC(TM) to detect its expression in vitro.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Application Notes:
Western Blot (1-2ug/ml),,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 2
Formalin-fixed, paraffin-embedded human tonsil stained with Protein Kinase C ? Mouse Monoclonal Antibody (133).
Formalin-fixed, paraffin-embedded human tonsil stained with Protein Kinase C ? Mouse Monoclonal Antibody (133).
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