Recombinant PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein) Antibody, Clone: [PMEPA1/6421R], Rabbit, Monoclonal

Product Overview

• Article Name: Recombinant PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein) Antibody, Clone: [PMEPA1/6421R], Rabbit, Monoclonal
• Biozol Catalog Number: NBT-56937-RBM11-P1
• Supplier Catalog Number: 56937-RBM11-P1
• Alternative Catalog Number: NBT-56937-RBM11-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Rabbit
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human
• Immunogen: Recombinant full-length human PMEPA1 protein
• Alternative Names: PMEPA, PMEPA1, Prostate transmembrane protein, androgen induced 1, Solid tumor-associated 1 protein, STAG1, TMEPAI, Transmembrane prostate androgen-induced protein, Transmembrane, prostate androgen induced RNA

Product Description

PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [PMEPA1/6421R]
• Molecular Weight: 32kDa
• NCBI: 56937
• UniProt: Q969W9
• Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Images

Formalin-fixed, paraffin-embedded human prostate carcinoma stained with PMEPA1 Recombinant Rabbit Monoclonal Antibody (PMEPA1/6421R).

Formalin-fixed, paraffin-embedded human prostate carcinoma stained with PMEPA1 Recombinant Rabbit Monoclonal Antibody (PMEPA1/6421R).

SDS-PAGE Analysis of Purified PMEPA1 Recombinant Rabbit Monoclonal (PMEPA1/6421R). Confirmation of Purity and Integrity of Antibody.

Western Blot Analysis of Human Prostate tissue lysate using PMEPA1 / TMEPAI Recombinant Rabbit Monoclonal Antibody (PMEPA1/6421R).