Scm-Related Gene Containing Four Mbt Domains 2, Scm-Like With 4 MBT Domains Protein 2, KIAA1617
The SFMBT2 (Scm-like with four MBT domains 2) gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene. Sfmbt2 is a Polycomb group (PcG) gene that maps to the proximal region of Chromosome 2, and is a putative imprinted gene. Sfmbt2 is the first imprinted gene within this region to be identified. Studies indicate that six different translocations involving proximal chromosome 2 results in lethality when present as a maternal uniparental duplication.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Flow Cytometric Analysis of PFA-fixed HeLa cells. SFMBT2 Mouse Monoclonal Antibody (PCRP-SFMBT2-2E12) followed by goat anti-mouse IgG-CF488 (blue), unstained cells (red).
SDS-PAGE Analysis of Purified SFMBT2 Mouse Monoclonal Antibody (PCRP-SFMBT2-2E12) Confirmation of Purity and Integrity of Antibody.
Immunofluorescence Analysis of PFA-fixed HeLa cells stained using SFMBT2 Mouse Monoclonal Antibody (PCRP-SFMBT2-2E12) followed by goat anti-mouse IgG-CF488 (green). CF640R phalloidin (red).
Analysis of Protein Array containing more than 19,000 full-length human proteins using SFMBT2 Mouse Monoclonal Antibody (PCRP-SFMBT2-2E12). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SDs) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SDs) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
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