Recombinant fragment (around aa1-100) of human BAX protein (exact sequence is proprietary)
Alternative Names:
Apoptosis regulator BAX cytoplasmic isoform beta, Apoptosis regulator BAX membrane isoform alpha, Bax isoform psi, Bax protein cytoplasmic isoform delta, Bax protein cytoplasmic isoform gamma, Bax zeta, Bcl-2-like protein 4, BCL2 associated X protein omega, BCL2 associated X protein transcript variant delta2, BCL2L4
Recognizes a protein of 21,AOkDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis of Purified BAX Recombinant Rabbit Monoclonal Antibody (BAX/8960R). Confirmation of Purity and Integrity of Antibody
Western Blot Analysis of Intestine and Lung tissue lysates of different species using Bax Recombinant Rabbit Monoclonal Antibody (BAX/8960R).
Western Blot Analysis of Human Intestine, Human Lung, A549 and MCF7 lysates using Bax Recombinant Rabbit Monoclonal Antibody (BAX/8960R).
Western Blot Analysis of A-549 cell lysate using Bax Recombinant Rabbit Monoclonal Antibody (BAX/8960R).
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