ACE2 / Angiotensin I Converting Enzyme 2 Antibody, IgG1, Clone: [ACE2/7203], Mouse, Monoclonal

Product Overview

• Article Name: ACE2 / Angiotensin I Converting Enzyme 2 Antibody, IgG1, Clone: [ACE2/7203], Mouse, Monoclonal
• Biozol Catalog Number: NBT-59272-MSM3-P0
• Supplier Catalog Number: 59272-MSM3-P0
• Alternative Catalog Number: NBT-59272-MSM3-P0-20
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: ELISA, IHC, WB
• Species Reactivity: Human
• Immunogen: Recombinant fragment (around aa1-300) of human ACE2 (exact sequence is proprietary)
• Alternative Names: ACE related carboxypeptidase, ACE2, ACEH, Angiotensin converting enzyme 2, Angiotensin converting enzyme like protein, Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2, Angiotensin-converting enzyme homolog, EC 3.4.17, DKFZP434A014, Metalloprotease MPROT15, Processed angiotensin-converting enzyme 2

Product Description

Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II toangiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage ofangiotensin II, may be an important regulator of heart function. By cleavage of angiotensin II, may also have a protective role in acute lung injury. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SL6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [ACE2/7203]
• Molecular Weight: 92kDa
• Isotype: IgG1
• NCBI: 59272
• UniProt: Q9BYF1
• Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.