Recombinant Pulmonary Surfactant-Associated Protein D (SFTPD) Antibody, IgG1, Clone: [rSFTPD/8065], Mouse, Monoclonal

Product Overview

• Article Name: Recombinant Pulmonary Surfactant-Associated Protein D (SFTPD) Antibody, IgG1, Clone: [rSFTPD/8065], Mouse, Monoclonal
• Biozol Catalog Number: NBT-6441-MSM11-P1ABX
• Supplier Catalog Number: 6441-MSM11-P1ABX
• Alternative Catalog Number: NBT-6441-MSM11-P1ABX-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human
• Immunogen: Recombinant fragment (around aa200-375) of human SFTPD protein (exact sequence is proprietary)
• Alternative Names: COLEC7, Collectin-7, Lung surfactant protein D, PSP-D Surfactant protein D, PSPD, Pulmonary surfactant associated protein PSP-D, SFTP 4, SFTP4, SFTPD, SP-D, Surfactant associated protein pulmonary 4

Product Description

Pulmonary surfactant is primarily responsible for lowering the surface tension at the air-liquid interface in the alveoli, a process that is essential for normal respiration. Pulmonary surfactant is a mixture of phospholipids and proteins, including four distinct surfactant-associated proteins (SPs), SP-A, SP-B, SP-C, SP-D. SP-B and SP-C are predominantly hydrophobic proteins that associate with lipids to promote the absorption of surfactant phospholipids and to reduce the surface tension in the alveoli. SP-A and SP-D are large multimeric proteins belonging to the family of calcium-dependent lectins, designated Collectins, which contribute to the innate immune system. Both SP-A and SP-D have been shown to protect against microbial challenge through binding to the lipid components of the bacterial cell wall and facilitating the rapid removal of microbials.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [rSFTPD/8065]
• Molecular Weight: 43kDa
• Isotype: IgG1
• NCBI: 6441
• UniProt: P35247
• Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Images

Western blot analysis of COLO38 cell lysate using SFTPD Mouse Recombinant Monoclonal Antibody (rSFTPD/8065).

Formalin-fixed, paraffin-embedded human lung stained with Surfactant Protein D Recombinant Mouse Monoclonal (rSFTPD/8065). Inset: PBS instead of primary antibody, secondary only negative control.

SDS-PAGE Analysis of Purified SFTPD Recombinant Mouse Monoclonal Antibody (rSFTPD/8065). Confirmation of Purity and Integrity of Antibody.