CDw75 (B-Cell Marker) Antibody, IgM, Clone: [LN-1], Mouse, Monoclonal

Product Overview

• Article Name: CDw75 (B-Cell Marker) Antibody, IgM, Clone: [LN-1], Mouse, Monoclonal
• Biozol Catalog Number: NBT-6480-MSM1-P1
• Supplier Catalog Number: 6480-MSM1-P1
• Alternative Catalog Number: NBT-6480-MSM1-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: FC, IF, IHC
• Species Reactivity: Human
• Immunogen: Nuclei from pokeweed mitogen-stimulated peripheral blood lymphocytes.
• Alternative Names: 6-sialyltransferase 1 (6-ST1), Alpha 2,6 ST1, Beta galactoside alpha 2,6 sialyltransferase 1, CMP N acetylneuraminate beta galactosamide alpha 2,6 sialyltransferase 1, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2, SIAT1, ST6 beta galactosamide alpha 2,6 sialyltranferase 1, ST6Gal I, ST6N

Product Description

Recognizes a neuraminidase-sensitive sialoprotein (CDw75), present on cell membrane and cytoplasm of germinal center B-cells and derived lymphomas. This MAb reacts with RBC precursors of bone marrow, ductal and ciliated epithelial cells of kidney, breast, prostate, pancreas, lung, and with glioblastomas, astrocytomas, and Reed Sternberg cells in lymphocyte predominant Hodgkin s disease. It is shown to be a helpful antibody for ascribing a B-cell phenotype in known lymphoid tissues.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [LN-1]
• Molecular Weight: 46kDa
• Isotype: IgM
• NCBI: 6480
• UniProt: P15907
• Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by PEG precipitation. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Images

Formalin-fixed, paraffin-embedded normal human spleen tissue stained with CDw75 Mouse Monoclonal Antibody (LN-1).

Surface staining of human lymphocytes with CDw75 Mouse Monoclonal Antibody (LN-1) (red) and isotype control (green). PPI negative population analyzed.

Immunofluorescence Analysis of MeOH-fixed HeLa cells labeled with CDw75 Mouse Monoclonal Antibody (LN-1) followed by goat anti-Mouse IgG-CF488 (Green). The nuclear counterstain is Reddot (Red).