Melanosome gp100 / PMEL17 / SILV (Melanoma Marker) Antibody, IgG2b, Clone: [SPM286], Mouse, Monoclonal

Product Overview

• Article Name: Melanosome gp100 / PMEL17 / SILV (Melanoma Marker) Antibody, IgG2b, Clone: [SPM286], Mouse, Monoclonal
• Biozol Catalog Number: NBT-6490-MSM2X-P1
• Supplier Catalog Number: 6490-MSM2X-P1
• Alternative Catalog Number: NBT-6490-MSM2X-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: FC, IF, IHC
• Species Reactivity: Equine, Human
• Immunogen: Membranes from a human melanoma metastasis
• Alternative Names: 95kDa melanocyte-specific secreted glycoprotein, M-beta, Melanocyte lineage specific antigen GP100, Melanocyte protein Pmel 17, Melanoma associated ME20 antigen, Melanosomal matrix protein17, p100, p26, PMEL17, Premelanosome protein, Secreted melanoma-associated ME20 antigen, SILV, Silver homolog

Product Description

By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.This Mab labels formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [SPM286]
• Molecular Weight: 90-100kDa
• Isotype: IgG2b
• NCBI: 6490
• UniProt: P40967
• Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Images

Formalin-fixed, paraffin-embedded human Melanoma stained with gp100 Monoclonal Antibody (SPM286).

Formalin-fixed, paraffin-embedded human Melanoma stained with gp100 Monoclonal Antibody (SPM286).