Blepharophimosis epicanthus inversus and ptosis 1, BPES 1, BPES, BPES1, Epicanthus inversus and ptosis 1, Forkhead box protein L2, Forkhead transcription factor FOXL2, PFRK, PINTO, PITUITARY FORKHEAD FACTOR, POF3
FOXL2 is a critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. It prevents trans-differentiation of ovary to testis through transcriptional repression of the sertoli cell-promoting gene SOX9. FOXL2 is mainly expressed in ovary, parathyroid gland and sex cord-stromal tumors. FOXL2 is generally used for diagnosis of sex cord-stromal tumors with Inhibin, Calretinin and SF-1.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.