StAR (Steroidogenic Acute Regulator) (Leydig Cell Marker) Antibody, IgG1, Clone: [STAR/3976], Mouse, Monoclonal

Catalog Number: NBT-6770-MSM6-P1ABX
Article Name: StAR (Steroidogenic Acute Regulator) (Leydig Cell Marker) Antibody, IgG1, Clone: [STAR/3976], Mouse, Monoclonal
Biozol Catalog Number: NBT-6770-MSM6-P1ABX
Supplier Catalog Number: 6770-MSM6-P1ABX
Alternative Catalog Number: NBT-6770-MSM6-P1ABX-100
Manufacturer: NeoBiotechnologies
Host: Mouse
Category: Antikörper
Application: IHC
Species Reactivity: Human
Immunogen: Recombinant fragment (around aa 39-108) of human STAR protein (exact sequence is proprietary)
Alternative Names: Cholesterol trafficker, Luteinizing hormone induced protein, Mitochondrial steroid acute regulatory protein, StAR, StAR related lipid transfer (START) domain containing 1, StARD1, START domain-containing protein 1, Steroid acute regulatory protein, Steroidogenic acute regulator (STAR), Steroidogenic acute regulatory protein mitochondrial
Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone. OOIt is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.
Clonality: Monoclonal
Clone Designation: [STAR/3976]
Molecular Weight: 30kDa
Isotype: IgG1
NCBI: 6770
UniProt: P49675
Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human adrenal gland stained with StAR Mouse Monoclonal Antibody (STAR/3976).
SDS-PAGE Analysis of Purified StAR Mouse Monoclonal Antibody (STAR/3976). Confirmation of Purity and Integrity of Antibody.