Recombinant CD147 / BSG / EMMPRIN / Neurothelin Antibody, IgG1, Clone: [rAB1843], Mouse, Monoclonal

Product Overview

• Article Name: Recombinant CD147 / BSG / EMMPRIN / Neurothelin Antibody, IgG1, Clone: [rAB1843], Mouse, Monoclonal
• Biozol Catalog Number: NBT-682-MSM26-P1
• Supplier Catalog Number: 682-MSM26-P1
• Alternative Catalog Number: NBT-682-MSM26-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human
• Immunogen: Recombinant human BSG protein
• Alternative Names: 5A11 Antigen, 5F7, Basigin, Blood brain barrier HT7 antigen BSG, Extracellular Matrix Metalloproteinase Inducer (EMMPRIN), Leukocyte Activation Antigen M6, Neurothelin, OK Blood Group Antigen, TCSF, Tumor Cell-derived Collagenase Stimulatory Factor

Product Description

This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [rAB1843]
• Molecular Weight: 35kDa (non-reduced), 40kDa (reduced)
• Isotype: IgG1
• NCBI: 682
• UniProt: P35613
• Form: 200ug/ml of Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Images

SDS-PAGE Analysis of Purified CD147 / Basigin Recombinant Mouse Monoclonal Antibody (rAB1843). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human placenta stained with CD147 / Basigin Recombinant Mouse Monoclonal Antibody (rAB1843). Inset: PBS instead of primary antibody, secondary only negative control.