Recombinant fragment (around aa 224-313) of human Synaptophysin (SYP) protein (exact sequence is proprietary)
Alternative Names:
Major synaptic vesicle protein p38, MRX96, MRXSYP, Syn p38, Syp, SYPH
This recombinant mouse monoclonal antibody recognizes a protein of 38kDa that is identified as synaptophysin. It is an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel.This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human pancreas stained with Synaptophysin Recombinant Mouse Monoclonal Antibody (rSYP/8807). Inset: PBS instead of primary antibody, secondary only negative control.
SDS-PAGE Analysis of Purified Synaptophysin Recombinant Mouse Monoclonal Antibody (rSYP/8807). Confirmation of Purity and Integrity of Antibody.
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