Recombinant Synaptophysin (Neuroendocrine Marker) Antibody, Clone: [MSVA-462R], Rabbit, Monoclonal

Product Overview

• Article Name: Recombinant Synaptophysin (Neuroendocrine Marker) Antibody, Clone: [MSVA-462R], Rabbit, Monoclonal
• Biozol Catalog Number: NBT-6855-RBM25-P0
• Supplier Catalog Number: 6855-RBM25-P0
• Alternative Catalog Number: NBT-6855-RBM25-P0-20
• Manufacturer: NeoBiotechnologies
• Host: Rabbit
• Category: Antikörper
• Application: IHC
• Species Reactivity: Human
• Immunogen: Recombinant fragment (around aa 274-313) of human Synaptophysin (SYP) protein (exact sequence is proprietary)
• Alternative Names: Major synaptic vesicle protein p38, MRX96, MRXSYP, Syn p38, Syp, SYPH

Product Description

This recombinant rabbit monoclonal antibody recognizes a protein of 38kDa that is identified as synaptophysin. It is an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [MSVA-462R]
• Molecular Weight: 38kDa
• NCBI: 6855
• UniProt: P08247
• Form: Ab produced in HEK293 cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide.

Images

Synaptophysin Rabbit Recombinant Monoclonal Antibody (MSVA-462R) tested on many normal and cancer tissues. The immunohistochemistry staining in these tissues aligns with the expression data in Human Protein Atlas.