Trefoil factor 2 / TFF2 Antibody, IgM, Clone: [GE16C], Mouse, Monoclonal
Catalog Number:
NBT-7032-MSM1-P1
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| Article Name: | Trefoil factor 2 / TFF2 Antibody, IgM, Clone: [GE16C], Mouse, Monoclonal |
| Biozol Catalog Number: | NBT-7032-MSM1-P1 |
| Supplier Catalog Number: | 7032-MSM1-P1 |
| Alternative Catalog Number: | NBT-7032-MSM1-P1-100 |
| Manufacturer: | NeoBiotechnologies |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | ELISA |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide corresponding to a 16-amino acid C-terminal sequence of the human Trefoil factor 2. |
| Alternative Names: | SML1, SP, Spasmolysin, Spasmolytic polypeptide, TFF2, trefoil factor 2 (spasmolytic protein 1), Trefoil factor 2, Trefoil factor 2 precursor |
| Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa. pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. The gene encoding pS2 maps to human chromosome 21q22.3. |
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