Enhancer of split groucho 1 (ESG1), Enhancer of split groucho-like protein 1, GRG1, TLE1, Transducin like enhancer of split 1, Transducin-like enhancer protein 1
Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein1 (TLE1) is a protein that isencoded by theTLE1 gene and is involved in control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis of Purified TLE1 Recombinant mouse Monoclonal Antibody (rTLE1/13032). Confirmation of Purity and Integrity of Antibody.
Formalin-fixed, paraffin-embedded human endometrium stained with TLE1 Recombinant Rabbit Monoclonal Antibody (rTLE1/13032). Inset: PBS instead of primary antibody, secondary only negative control.
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