von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) Antibody, IgG1, Clone: [F8/86], Mouse, Monoclonal
Biozol Catalog Number:
NBT-7450-MSM6-P0
Supplier Catalog Number:
7450-MSM6-P0
Alternative Catalog Number:
NBT-7450-MSM6-P0-20,NBT-7450-MSM6-P0-100
Manufacturer:
NeoBiotechnologies
Host:
Mouse
Category:
Antikörper
Application:
IHC
Species Reactivity:
Human
Immunogen:
von Willebrand Factor isolated from human plasma
Alternative Names:
Coagulation Factor VIII, Factor VIII Related Antigen, F8VWF, von Willebrand Antigen 2, von Willebrand Disease (vWD)
von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Application Notes:
Immunohistochemistry (Formalin-fixed) (0.1-0.2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes), Optimal dilution f
Formalin-fixed, paraffin-embedded human Tonsil stained with vWF Mouse Monoclonal Antibody (F8/86).
Formalin-fixed, paraffin-embedded human Tonsil stained with vWF Mouse Monoclonal Antibody (F8/86).
SDS-PAGE Analysis of Purified vWF Mouse Monoclonal Antibody (F8/86). Confirmation of Purity and Integrity of Antibody.
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