Recognizes a glycoprotein of ~200kDa, identified as carbonic anhydrase IX (CAIX/gp200).In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowmans capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Western Blot Analysis of Human Stomach, Mouse Stomach, Rat Stomach, Hamster Stomach and Guinea pig Stomach tissue lysates using CA9 Recombinant Mouse Monoclonal Antibody (rCA9/9937).
Western Blot Analysis of Human Stomach tissue cell lysate using CA9 Recombinant Mouse Monoclonal Antibody (rCA9/9937).
SDS-PAGE Analysis of Purified CA9 Recombinant Mouse Monoclonal Antibody (rCA9/9937). Confirmation of Purity and Integrity of Antibody.
Formalin-fixed, paraffin-embedded human stomach stained with CA9 Recombinant Mouse Monoclonal Antibody (rCA9/9937). Inset: PBS instead of primary antibody, secondary only negative control.
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